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产品目录

重组人E钙粘蛋白(上皮型钙黏附素)(E-Cadherin)(CDH1)图片
产品货号:
JN1529
中文名称:
重组人E钙粘蛋白(上皮型钙黏附素)(E-Cadherin)(CDH1)
英文名称:
Recombinant Human Cadherin-1/E-Cadherin/CDH1
产品规格:
10μg|50μg|500μg|1mg
发货周期:
1~3天
产品价格:
询价
本品由我们的哺乳动物细胞表达系统制备而成,目的基因编码的Asp155-Ile707在C端含有His标签。

E-cadherin质量控制:>95%(还原性SDS-PAGE)

E-cadherin制剂:冻干品

E-cadherin保存
冻干蛋白置于-20℃以下可长期保存,室温条件下可稳定保存3周。
复溶蛋白溶液可在4~7℃保存2~7天,可分装后置于-20℃保存三个月。

E-cadherin复溶
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后,请根据用量分装冻存,避免反复冻融。

关于E-cadherin
E-Cadherin is a classical member of the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region, and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid, and ovarian cancers. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells, and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. Also, E-Cadherin has a potent invasive suppressor role and it is a ligand for integrin alpha-E/beta-7.
相关搜索:重组人E钙粘蛋白(上皮型钙黏附素)(E-Cadherin)(CDH1)Recombinant Human Cadherin-1/E-Cadherin/CDH1
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